Abstract

Review Article

Possible links between consumption of A1 “like” milk And Type 1 Diabetes (T1D)

Mohammad Raies Ul Haq*, Asima H and Aarif B

Published: 27 June, 2019 | Volume 3 - Issue 1 | Pages: 010-016

During the last three decades, there has been an interesting debate on the intake of A1 ‘like” milk and incidence of type 1 diabetes (T1D) in genetically predisposed individuals. The epidemiological, ecological and case-control studies have concrete pieces of evidences in favor of the hypothesis that is further supported by animal trials in mice and rat and in vitro trials on cell lines. But on the other hand, European Food Safety Authority reported that there isn’t sufficient data to draw a final recommendation at this stage in terms of contradictory results, lack of cause-effect relationship and being a mere suggestive evidence [1]. However, the report itself states that these studies are strong enough to formulate a concrete hypothesis and further research is needed to confirm the same. Keeping in view the published data in favor of the hypothesis and the counter-arguments, it is suggested that further research with well-designed animal and in vitro trials with intact proteins and peptides is needed to fully confirm the hypothesis. Until the issue is fully resolved, it’s the personal choice of the individuals at risk to T1D (genetically predisposed) to either remove A1 “like” or increase the A2 “like” milk from their diet. 

Read Full Article HTML DOI: 10.29328/journal.afns.1001018 Cite this Article Read Full Article PDF

Keywords:

β-casein; A1 β-casein; A2 β-casein; Type 1 diabetes

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