Research Article

Changes in Serum Markers of Atherogenesis and Hematological Profile after the consumption of Quail eggs

Ekpenyong CE*, Patrick ES and Akpan KS

Published: 10 May, 2017 | Volume 1 - Issue 1 | Pages: 001-011

Previous studies suggest that diets with more eggs than is recommended may be used as part of a healthy diet in some countries. However, whether quail egg diets could form part of such diet has not been explored. The aim of the present study is to evaluate the effect of quail egg consumption on serum markers of atherogenesis and hematological parameters in healthy volunteers. Thirty adult subjects participated in this study after ascertaining their baseline health status. They were fed 3 eggs per day and 8hourlyfor 30 days. They were evaluated for serum levels of cholesterol sub-fractions, AIP and hematological parameters at days 0, 10 and 30 after the consumption of quail eggs. At day10, serum levels of cholesterol sub-fractions (TG, HDL-C and LDL-C) were not significantly (p>0.05) different from the corresponding values at baseline. Serum levels of VLDL-C and calculated AIP significantly (p<0.05) decreased compared to the levels at baseline. At day 30, serum levels of HDL-C, TG and VLDL-C significantly (p<0.05) increased, while LDL-C and AIP significantly decreased. Also, total RBC, HB, PCV, MCV, MCH and MCHC were not significantly different from the levels at baseline. At day 30, RBC, PCV and HB significantly (p<0.05) increased compared to the levels at baseline, while MCV, MCH and MCHC were not significantly (p>0.05) different from the baseline values.

Indeed, long-term consumption of quail egg may be associated with improvement in serum markers of atherogenesis and hematological parameters due to its varied nutrient constituents and their activities.

Read Full Article HTML DOI: 10.29328/journal.afns.1001001 Cite this Article Read Full Article PDF


Quail egg; Atherosclerosis; Cardiovascular disease; Human


  1. Voutilainen S, Nurmi T, Mursu J, Rissanen TH. Carotenoids and Cardiovascular health. Am J Clin Nutr. 2006; 83: 1265-1271. Ref.: https://goo.gl/il0F51
  2. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006; 3: e442. Ref.: https://goo.gl/YHtK2i
  3. Stamler J. Established major coronary heart disease epidemiology: from Aetiology to Public Health, Edited by M. Marmot & P. Elliot, New York. Oxford University Press. 1993; 35-66. Ref.: https://goo.gl/m6dO80
  4. Singh RB, Niaz MA, Ghosh S. Hyperlipidemic and antioxidant effects of Commiphora mukul as an adjunct to dietary therapy in patients with hypercholesterolemia. Cardiovasc Drugs Ther. 1993; 8: 659-664. Ref.: https://goo.gl/XBFbGo
  5. Tunsaringkarn T, Tungjaroenchai W, Sirwong W. Nutrient benefits of quail (coturnix japonica) eggs. Int J Sci Res Pub. 2013; 3: 1-8. Ref.: https://goo.gl/AHgm2p
  6. Dobrass F. Quail eggs farming in Nigeria. 2012.
  7. Oguwike FN, Ebede S, Offor CC, Olisah MC. Activities of quail eggs in female anemic hypertensive subjects in Ogwa Imo State, Nigeria. IOSR J Dental Med Sci. 2014; 13: 106-109. Ref.: https://goo.gl/t6VqgI
  8. Lalwani P. Quail egg nutrition. 2017. Ref.: https://goo.gl/J4pmYJ
  9. Anca T, Vacaru-opris I, Teusan V. Aspects regarding some morphological values of the domestic quail eggs (Coturix japonica). Lucr Stiint Zooteh Biotech. 2008; 41: 709-716. Ref.: https://goo.gl/V1ZYTz
  10. Adeniyi OT. Effect of Japanese quail egg (coturnix Japonica) egg supplementation on poloxamer 407-induced hyperlipidaemic Wister rats. An MSC Thesis. 2014. Ref.: https://goo.gl/ZXxHEi
  11. Lontchi-Yimagou E, Tanya A, Tchankon C, Ngondi J, Oben J. Metabolic effect of quail eggs in diabetes-induced rats: comparison with chicken eggs. Food Nutr Res. 2016; 60. Ref.: https://goo.gl/vK0j8N
  12. Techakriengkrai T, Klangjareonchai T, Pakpeankitwattan V, Sritara P, Roongpisuthipong C. The effect of ingestion of eggs and low density lipoprotein (LDL) oxidation on serum lipid profile in hypercholesterolemic women. Songklanakarin J Sci Technol. 2012; 34: 173-178. Ref.: https://goo.gl/Qmz1Wx
  13. Dobiasova M. AIP-atherogenic index of plasma as a significant predictor of cardiovascular risk: from research to practice. Vnitrni Lekarstvi. 2006; 52: 64-71. Ref.: https://goo.gl/OIfwLi
  14. Kastelein JJP, van der Steeg WA, Holme I, Gaffney M, Cater NB, et al. Lipids, apolipoproteins and their ratios in relation to cardiovascular events with statin treatment. Circulation. 2008; 117: 3002-3009. Ref.: https://goo.gl/rY4ROi
  15. Grundy SM. Oxidized LDL and atherogenesis: relation to risk factors for coronary heart disease. Clin Cardiol. 1993; 16: 3-5. Ref.: https://goo.gl/Ipefdn
  16. Ekpenyong CE. Micronutient vitamin deficiencies and cardiovascular disease risk: advancing current understanding. Eur J Prevent Med. 2017; 5: 1-18. Ref.: https://goo.gl/c7bktg
  17. Woollet LA, Spady DK, Dietschy JM. Saturated and unsaturated fatty acids independently regulate low density liporpotien receptor activity and production rate. J Lipid Res. 1992; 33: 77-88. Ref.: https://goo.gl/MQBwxt
  18. The Lipid Research Clinic-Coronary Prevention Trial Results (LRC-CPTR). II. The relationship of reduction of incidence of coronary heart disease. JAMA. 1984. 251: 365-374. Ref.: https://goo.gl/i99ioe
  19. Kannel WB, Castelli WP, Gordon T. Cholesterol in the production of atherosclerotic disease: New perspectives in the Framingham study. Ann Inter Med. 1979; 90: 85-91. Ref.: https://goo.gl/SmAvaF
  20. Stahl W, Sies H. Physical quenching of singlet oxygen and cis-trans isomerization of carotinoids. Ann NY Acad Sci. 1993; 691: 10-19. Ref.: https://goo.gl/QeEm2q
  21. Muscogiuri G, Sorice GP, Ajjan R, Mezza T, Pilza S, et al. Can vitamin D deficiency cause diabetes and cardiovascular disease? Present evidence and future perspectives. Nutr metab Cardiovascular Dis. 2012; 22: 18-27. Ref.: https://goo.gl/AhfMT6
  22. Ranasinghe P, Wathurapatha WS, Ishara MH, Jayawardana R, Galappatthy P, et al. Effects of zinc supplementation on serum lipids; a systematic review and meta-analysis. Nutr Metab. 2015; 12: 26. Ref.: https://goo.gl/qzRRUz
  23. What are the benefits of quail eggs? 1999-2012. Ref.: https://goo.gl/f0uLfR
  24. Ekpenyong CE, Daniel NE. Roles of diets and dietary factors in the pathogenesis, management and prevention of abnormal serum uric acid levels. J PharmaNutr. 2014; 3: 29-45. Ref.: https://goo.gl/i8Yz9E
  25. Gordon T, Castelli WP, Hjortland Mc, et al. High density lipoprotein as a protective factor against coronary heart disease. The Framingham study. Am J Med. 1977; 62: 707-714. Ref.: https://goo.gl/Xa8Pqi
  26. Wilson PW, Abbott RD, Castelli WP. High density lipoprotein cholelsterol and mortality. The Framingham heart study. Arteriosclerosis. 1988; 8: 737-741. Ref.: https://goo.gl/584kht
  27. Castelli WP, Garrison RJ, Wilson PWF, et al. Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham study. JAMA. 1986; 256: 2835-2838. Ref.: https://goo.gl/fEQsOh
  28. Barter P. The role of HDL-cholesterol in preventing atherosclerotic disease. European Heart Journal Supplements. 2005; 7: F4-F8. Ref.: https://goo.gl/rGbF7n
  29. Jailal I, Freeman DA, Grundy SM. Varying susceptibility of different low density lipoprotein to oxidative modification. Arteriosc Thrombosis. 1991; 11: 482-488. Ref.: https://goo.gl/A602ce
  30. Feki M, Souissi M, Mokhtar E, Hsairi M, Kaabachi N,et al. Vitamin E and Coronary Heart Disease in Tunisians. Clin Chem. 2000; 46: 1401-1405. Ref.: https://goo.gl/UcGWHi
  31. Sikarwar MS, Patil MB. Antihyperlipidemic effect of ethanolic extraction of Hibiscus rosa Sinensis flowers in hyperlidemic rats. RGUHS J Pharm Sci. 2011; 1: 117-122. Ref.: https://goo.gl/Dm5ozI


Figure 1

Figure 1

Figure 1

Figure 2

Figure 1

Figure 3

Figure 1

Figure 4

Figure 1

Figure 5

Figure 1

Figure 6

Similar Articles

Recently Viewed

Read More

Most Viewed

Read More

Help ?